Synergistic effects of multiple natural products in pancreatic cancer cells
نویسندگان
چکیده
منابع مشابه
Stem cells, cancer stem-like cells, and natural products.
Somatic stem cells can be found in many rapidly regenerating tissues, e.g., the skin, gastrointestinal mucosa, and hematopoietic system, but are also present at low numbers in non-regenerative organs such as the heart and brain. In these organs, somatic stem cells aid in normal tissue homeostasis and repair after injury as well as self-renewal and the generation of specific progenitor cells dur...
متن کاملTargeting Multiple Myeloma Cancer Stem Cells with Natural Products - Lessons from Other Hematological Malignancies.
Multiple myeloma is characterized by the accumulation of malignant plasma cells in the bone marrow. Multiple myeloma is the second most frequently diagnosed hematological malignancy, predominantly affecting the elderly. Despite recent advances in the development of novel therapies, multiple myeloma remains an incurable malignancy where the majority of patients relapse, develop resistance, and e...
متن کاملThe use of natural products to target cancer stem cells.
The cancer stem cell hypothesis has been used to explain many cancer complications resulting in poor patient outcomes including induced drug resistance, metastases to distant organs, and tumor recurrence. While the validity of the cancer stem cell model continues to be the cause of much scientific debate, a number of putative cancer stem cell markers have been identified making studies concerni...
متن کاملRadiosensitizing effects of Sestrin2 in PC3 prostate cancer cells
Objective(s): The stress-responsive genes of Sestrin family are recognized as new tumor suppressor genes in breast carcinoma, however, the function of Sestrin family in human prostate cancer is not clear. Ionizing radiation (IR) is known to induce Sestrin gene expression in breast cancer cells. However, the response of Sestrin to IR has not been reported in PC3 prostate cancer cells. Materials ...
متن کاملAntimicrobial effects of natural products
Natural products, such as plants and their components, have been used to treat and cure diseases all around the globe since ancient times, long before the discovery of current pharmaceuticals. Natural products have long been used for antiinflammatory, analgesic, and antipyretic remedies as well as alternatives for hormone replacement therapy. In this paper, an extensive review of the role of na...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Life Sciences
سال: 2008
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2008.06.017